Post Number 666 - Ooh!
I'm very jealous, Zakdog!
I had a similar road trip in 2004. We started by flying into San Fran, taking in Napa Valley, Lake Tahoe, Sacramento (no offense to anyone on the forum from this fine city, but if I didn't have friends that we visited there, I wouldn't have gone!), Yosemite, Mammoth Lakes, Mono Lake (well worth a visit on your itinerary), Death Valley, Grand Canyon, Las Vegas and then back to San Fran on a different loop.
Awesome trip - you'll have a ball. I only had a point and shoot at the time, but if I was repeat the trip I'd take everything I've got. You've got some of the most stunning scenery imaginable that you will be visiting and it's not worth compromising and risking not doing it justice.