I tested the 120-400 OS
here. The 150-500 OS is the same construction just with a different front-end. I was quite disappointed by the efficiency of the OS but different opinions on the web suggest that this might have been a QC-issue (not the first with a Sigma lens).
If the OS works properly the stabilization could be very helpful when shooting the long end w/o tripod.
But if you normally carry a tripod with you you might like the non-stabilized older 170-500 version.
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Thomas (beware: Nikon-fanboy and moderator!)
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D300+assorted lenses