I had an incredibly bad experience while editing my first wedding last year where my Windows install ceased to boot due to some massive corruptions in my TIFFs I was working from. No viruses or anything like that, as I was able to remove the problematic TIFFs and the system worked as normal afterward. Needless to say, it was PSD from there on out.
However, I now avoid Photoshop like the plague because A) my exposures are far more consistent now and my processing in LR has improved immensely, B) I'm lazy and I like working in one piece of software as much as possible, and C) retouching is a soul-sucking endeavor.
PS - I only process RAW. The arguments for DNG conversion regarding lack of future file-type support of proprietary formats just don't stack up in my mind... It's not like one day someone will just come and take your older version of software away and make you replace it with something that doesn't support your RAW files. If support for CR2/NEF/etc. is really going to end, there will be some sort of heads up about it, giving you time to do all the converting you need to...
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